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The haunted loot cave voice line bears a striking resemblance to a line from Frank Herbert's novel Dune about deaths not being enough for a character named Yueh. Bungie has never confirmed whether the similarity was an intentional literary nod or coincidence.
Scattered throughout the Gnomeregan dungeon are collectible punch cards, each stamped with a string of binary code. Decode them and you'll find a set of silly, lore-flavoured in-jokes, including one that simply reads 'if you can read this, you're standing too close.'
Inside the Assassin Tomb beneath Santa Maria della Visitazione, if Ezio stares into the water near the first lever for about a minute, a cutscene plays showing a giant squid swimming past. Look again and a tentacle nearly slaps him.
When data-miners first located the coordinates for the game's hidden Golden Peyote, they found a comment left directly in GTA V's source code by Rockstar, ribbing the discoverer for starting the hunt on the wrong day of the week: 'he was wrong to start his hunt on Tuesday.'
